Time-frame sampling for 82Rb PET flow quantification: Towards standardization of clinical protocols

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Quantification of Myocardial Blood Flow in€Absolute Terms Using 82Rb PET Imaging

Fro Ev xR {S **C Mi Nu Ca Un Fin Tu Mi 17) QP rec ser an IN OBJECTIVES The purpose of this study was to compare myocardial blood flow (MBF) and myocardial flow reserve (MFR) estimates from rubidium-82 positron emission tomography (Rb PET) data using 10 software packages (SPs) based on 8 tracer kinetic models. BACKGROUND It is unknown how MBF and MFR values from existing SPs agree for Rb PET. ME...

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Quantification of myocardial blood flow with 82Rb: Validation with 15O-water using time-of-flight and point-spread-function modeling

BACKGROUND We quantified myocardial blood flow with (82)Rb PET using parameters of the generalized Renkin-Crone model estimated from (82)Rb and (15)O-water images reconstructed with time-of-flight and point spread function modeling. Previous estimates of rubidium extraction have used older-generation scanners without time-of-flight or point spread function modeling. We validated image-derived i...

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Optimally Repeatable Kinetic Model Variant for Myocardial Blood Flow Measurements with 82Rb PET

Purpose. Myocardial blood flow (MBF) quantification with 82Rb positron emission tomography (PET) is gaining clinical adoption, but improvements in precision are desired. This study aims to identify analysis variants producing the most repeatable MBF measures. Methods. 12 volunteers underwent same-day test-retest rest and dipyridamole stress imaging with dynamic 82Rb PET, from which MBF was quan...

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Repeatability of rest and hyperemic myocardial blood flow measurements with 82Rb dynamic PET.

UNLABELLED The repeatability of rest and hyperemic myocardial blood flow (MBF) measurements using 82Rb PET has not been evaluated. The aim of this study was to investigate the short-term repeatability of such measurements. METHODS Fifteen healthy volunteers underwent rest and pharmacologic stress 82Rb PET, repeated 60 min apart. RESULTS There was no significant difference in repeated rest M...

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ژورنال

عنوان ژورنال: Journal of Nuclear Cardiology

سال: 2017

ISSN: 1071-3581,1532-6551

DOI: 10.1007/s12350-017-0981-1